Compound ID | 2156
SLAP-S25
Class: Antimicrobial peptide
| Agent Type: | Synthetic; Direct acting; Antibiotic adjuvant; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Membrane-active agent. Triggers membrane damage by binding to lipopolysaccharide in outer membrane and phosphatidylglycerol in cytoplasmic membrane |
| Description: | Synthetic compound; potentiates activity of antibacterial drugs including cefepime, colistin, ofloxacin, rifampicin, tetracycline, and vancomycin |
| Year first mentioned: | 2020 |
| Development status: | Experimental |
| External links: | |
| Citations: |
|
| Patent: | CN108467424B |
AntibioticDB is supported by GARDP.
If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions
The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.