Compound ID | 2159
SC5005
Class: Small molecule antibacterial agent
| Spectrum of activity: | Gram-positive |
| Details of activity: | Perturbation of the bacterial cytoplasmic membrane; eradicates S. aureus persisters and biofilm |
| Propensity to select resistant mutants: | No detectable resistance in S. aureus |
| Description: | Synthetic small molecule, derivative of sorafenib/ malonamide; demonstrated activity against MRSA in murine peritonitis model |
| Year first mentioned: | 2015 |
| Development status: | Experimental |
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