Compound ID | 2161

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S-MGB-364

Class: Small molecule antibacterial agent

Details of activity: Active against clinical Mycobacterium tuberculosis strain HN878 in macrophages; binds to the DNA as a dimer and inhibits relaxation of M. tuberculosis topoisomerase I
Description: Synthetic compound based on natural product distamycin
Year first mentioned: 2017
Development status: Experimental
External links:
PubMed link: https://pubmed.ncbi.nlm.nih.gov/35084027/
Citations:
  • https://academic.oup.com/jac/article/72/12/3334/4161409
  • https://academic.oup.com/jac/article/77/4/1061/6515318?searchresult=1

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