Compound ID | 2194

Update compound information

Chrysomycin A

Class: Natural product antibiotic

Details of activity: Active against Mycobacterium tuberculosis; speculated to bind to primase domain of topoisomerase I or to both the enzyme and the specific nucleotide sequences of DNA
Description: Natural product from Streptomyces sp.; coumarin scaffold; acts synergistically with ethambutol and ciprofloxacin
Year first mentioned: 1955
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 508.52
Iso. SMILES: C[C@@H]1[C@@H]([C@@]([C@H]([C@@H](O1)C2=C3C(=C(C=C2)O)C(=CC4=C3OC(=O)C5=C4C(=CC(=C5)C=C)OC)OC)O)(C)O)O
InChI Key: OMDANBMKOUVKAG-WZNMFJNZSA-N
Can. SMILES: C=CC1=CC2=C(C3=CC(=C4C(=CC=C(C4=C3OC2=O)[C@H]5[C@@H]([C@@](C)([C@H]([C@@H](C)O5)O)O)O)O)OC)C(=C1)OC
InChI: InChI=1S/C28H28O9/c1-6-13-9-16-20(18(10-13)34-4)15-11-19(35-5)22-17(29)8-7-14(21(22)23(15)37-27(16)32)24-26(31)28(3,33)25(30)12(2)36-24/h6-12,24-26,29-31,33H,1H2,2-5H3/t12-,24+,25+,26+,28-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/73468
Citation: https://www.nature.com/articles/s41429-022-00503-z

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.