Compound ID | 2214

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Mycomethoxin B

Synonym(s): 1-methoxyphenazine  |  methyl-6-methoxyphenazine-1-carboxylate  |  2,3-dimethoxy benzamide

Class: Natural product antibiotic

Agent Type: Natural product; Small molecule;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Unknown
Target Pathogen: Active against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi
Description: Natural product from Streptomyces luteireticuli NIIST-D75; synergistic effect individually with ciprofloxacin, limited activity alone; has a phenzine/ benzamide core
Year first mentioned: 1972
Development status: Experimental
Chemical structure(s):
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Molecular weight: 210.23
Iso. SMILES: COC1=CC=CC2=NC3=CC=CC=C3N=C21
InChI Key: ZYDGCYWJDWIJCS-UHFFFAOYSA-N
Can. SMILES: COC1=CC=CC2=C1N=C3C=CC=CC3=N2
InChI: InChI=1S/C13H10N2O/c1-16-12-8-4-7-11-13(12)15-10-6-3-2-5-9(10)14-11/h2-8H,1H3
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/76137
Citation: https://www.nature.com/articles/s41429-023-00600-7#Sec12

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