Compound ID | 2216

Update compound information

Longicatenamide

Class: Antimicrobial peptide

Agent Type: Natural product; Small molecule;
Spectrum of activity: Gram-positive
Mechanism of action: Unknown
Target Pathogen: Active against Bacillus subtilis
Description: Natural product from Streptomyces sp. KUSC_F05 when co-cultured with Tsukamurella pulmonis TP-B0596; no cytotoxicity observed in human fibrosarcoma HT1080 cells
Year first mentioned: 2021
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 742.86
Iso. SMILES: CC(C)CCC[C@H]1C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)NCC(=O)N1)CC2=CNC3=CC=CC=C32)[C@@H](CC(=O)O)O)CCCN)C(C)C
InChI Key: LDEUYUHPIUIRLG-NBFTVFEHSA-N
Can. SMILES: CC(C)CCC[C@H]1C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](CC(=O)O)O)C(=O)N[C@H](CC2=CNC3=C2C=CC=C3)C(=O)NCC(=O)N1
InChI: InChI=1S/C36H54N8O9/c1-19(2)9-7-12-24-33(50)43-30(20(3)4)35(52)41-25(13-8-14-37)34(51)44-31(27(45)16-29(47)48)36(53)42-26(32(49)39-18-28(46)40-24)15-21-17-38-23-11-6-5-10-22(21)23/h5-6,10-11,17,19-20,24-27,30-31,38,45H,7-9,12-16,18,37H2,1-4H3,(H,39,49)(H,40,46)(H,41,52)(H,42,53)(H,43,50)(H,44,51)(H,47,48)/t24-,25+,26+,27+,30+,31-/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/169492424
Citations:
  • https://pubmed.ncbi.nlm.nih.gov/36474967/
  • https://www.nature.com/articles/s41429-020-00400-3#Sec13

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