Compound ID | 2227
Rifaphenzine
Class: Rifampicin
| Details of activity: | Active against Mycobacterium tuberculosis; binds to Mtb RNA polymerase |
| Description: | Synthetic compound; combining 2,3 diamino phenazine (clofazimine precursor) and rifampicin core; non cytotoxic to human monocytic cell line THP-1 |
| Institute where first reported: | ICMR-National Institute for Research in Tuberculosis, Chennai, India |
| Year first mentioned: | 2021 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://www.nature.com/articles/s41598-020-80439-2#further-reading |
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