Compound ID | 2232

Update compound information

Tatiomicin

Class: Natural product antibiotic

Spectrum of activity: Gram-positive
Details of activity: Active against Staphylococcus and Streptococcus sp.; probably dissipates membrane potential
Propensity to select resistant mutants: No
Description: Natural product from Amycolatopsis sp. DEM30355; no activity against Candida spp.; a rishirilide scaffold
Year first mentioned: 2022
Development status: Experimental
Chemical structure(s):
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Molecular weight: 402.4
Iso. SMILES: O=C1[C@@H](C)[C@]2(O)[C@@](/C=C\C)(O)[C@]3(OC2=O)[C@H](O)C4=C(OC)C=CC(OC)=C4C=C31
InChI Key: XNIYSUYUZKIGJN-BCNFIMTMSA-N
Can. SMILES: C/C=C\[C@]1([C@]2([C@H](C)C(=O)C3=CC4=C(C(=CC=C4OC)OC)[C@H]([C@]31OC2=O)O)O)O
InChI: InChI=1S/C21H22O8/c1-5-8-19(25)20(26)10(2)16(22)12-9-11-13(27-3)6-7-14(28-4)15(11)17(23)21(12,19)29-18(20)24/h5-10,17,23,25-26H,1-4H3/b8-5-/t10-,17-,19-,20-,21-/m1/s1
External links:
Citation: https://www.nature.com/articles/s41598-022-18726-3#Sec1

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