Compound ID | 2233

Menaquinone Binding Antibiotic (MBA)

Class: Small molecule antibacterial agent

Spectrum of activity: Gram-positive
Details of activity: Active against Staphylococcus aureus and Mycobacterium tuberculosis; depolarises membrane
Description: Semisynthetic compound discovered by metagenomic searching of biosynthetic gene cluster predicted to encode menaquinone binders/ synthetic bioinformatic natural product (syn-BNP)
Year first mentioned: 2022
Development status: Experimental

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