Compound ID | 2243
g-D50
Synonym(s): a-T50
Class: Membrane-active agent
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Active against Staphylococcus aureus (g-D50) and Pseudomonas aeruginosa; disrupts cell membrane and dissipates membrane potential at sub-MIC concentrations |
| Description: | Synthetic compound; g-D50 has additive effects with beta-lactams, vancomycin, erythromycin, or ciprofloxacin and synergistic with silver sulfadiazine; a-T50 has synergistic effect with polymyxin and colistin |
| Year first mentioned: | 2023 |
| Development status: | Experimental |
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