Compound ID | 2257
Compound 10 HD5 analogue
Class: Antimicrobial peptide
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Active against ESKAPE pathogens; targets OmpA beta-barrel domain and LPS lipid A domain in Gram-negative outer membrane; also targets the 70S ribosome |
| Description: | Synthetic compound based on human defensin 5 |
| Year first mentioned: | 2022 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://www.pnas.org/doi/10.1073/pnas.2117283119#sec-2 |
AntibioticDB is supported by GARDP.
If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions
The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.