Compound ID | 226

Update compound information

DS-96

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-negative
Mechanism of action: Vaginal microbicide; targets the chlamydial lipooligosaccharide; also binds and neutralizes Gram-negative lipopolysaccharide
Target Pathogen: Active against Chlamydia trachomatis and Gram-negatives
Description: Synthetic alkylpolyamine; rationally designed with high affinity to Escherichia coli lipid A
Institute where first reported: Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA
Year first mentioned: 2008
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 483.86
Iso. SMILES: NCCCNCCCCNCCCNCCCNCCCCCCCCCCCCCCCC
InChI Key: BEBRHYPWEKUKTQ-UHFFFAOYSA-N
Can. SMILES: CCCCCCCCCCCCCCCCNCCCNCCCNCCCCNCCCN
InChI: InChI=1S/C29H65N5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-22-32-26-19-28-34-29-20-27-33-24-17-16-23-31-25-18-21-30/h31-34H,2-30H2,1H3
External links:
Citations:
  • https://experts.umn.edu/en/publications/pharmacokinetics-of-ds-96-an-alkylpolyamine-lipopolysaccharide-se
  • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068484/
  • https://www.ncbi.nlm.nih.gov/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Click%20on%20image%20to%20zoom&p=PMC3&id=4068484_zac0061428950001.jpg

    • AntibioticDB is supported by GARDP.

    If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

    The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.