Compound ID | 2272

Thuricin CD

Class: Antimicrobial peptide

Spectrum of activity: Gram-positive
Details of activity: Active against spore-forming clostridia and bacilli
Description: Natural product from a faecal sample Bacillus thuringiensis; compares favourably to metronidazole when tested on ex vivo distal colon C. difficile 001 infection model; does not kill beneficial Gram-positives in gut (ex. Lactobacillus casei 338 or Bifidobacterium lactis Bb12); two-component bacteriocin
Year first mentioned: 2010
Development status: Experimental

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