Compound ID | 2274

Hybrimycin B

Class: Aminoglycoside

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Staphylococcus aureus, Escherichia coli, Proteus vulgaris Klebsiella pneumoniae, Salmonella schottmuelleri
Description: Semisynthetic compound; produced by Streptomyces fradiae 3535 mutant blocked in deoxystreptamine synthesis then supplemented with 2-epistreptamine to produce analogue
Year first mentioned: 1969
Development status: Experimental

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