Compound ID | 2274
Hybrimycin B
Class: Aminoglycoside
| Agent Type: | Semisynthetic; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Unknown |
| Target Pathogen: | Active against Staphylococcus aureus, Escherichia coli, Proteus vulgaris Klebsiella pneumoniae, Salmonella schottmuelleri |
| Description: | Semisynthetic compound; produced by Streptomyces fradiae 3535 mutant blocked in deoxystreptamine synthesis then supplemented with 2-epistreptamine to produce analogue |
| Year first mentioned: | 1969 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://www.pnas.org/doi/epdf/10.1073/pnas.63.1.198 |
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