Compound ID | 228

KS100

Class: Antivirulence agent (T6SS inhibitor)

Spectrum of activity: Gram-negative
Details of activity: Type VI secretion system (T6SS) inhibition in Vibrio cholerae
Propensity to select resistant mutants: Yes
Description: thiohydrazides
Institute where first reported: Department of Clinical Microbiology, Clinical Bacteriology and Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden
Year first mentioned: 2014
Highest developmental phase: Preclinical
Development status: Active

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