Compound ID | 228
Class: Antivirulence agent (T6SS inhibitor)
Spectrum of activity: | Gram-negative |
Details of activity: | Type VI secretion system (T6SS) inhibition in Vibrio cholerae |
Propensity to select resistant mutants: | Yes |
Description: | thiohydrazides |
Institute where first reported: | Department of Clinical Microbiology, Clinical Bacteriology and Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden |
Year first mentioned: | 2014 |
Highest developmental phase: | Preclinical |
Development status: | Active |
External links: | |
Citation: | http://aac.asm.org/content/58/7/4123.full |