Compound ID | 2287
DCH
Class: Antibiofilm agent
| Spectrum of activity: | Gram-positive |
| Details of activity: | Active against Staphylococcus aureus and Staphylococcus epidermidis; inhibits biofilm formation; binds with methicillin-resistant Staphylococcus aureus ArgR |
| Description: | Synthetic compound; a bis-coumarin derivative; exhibited cytotoxicity against endothelial cells and cells from human embryonic myocardial tissue but at >50x MIC |
| Year first mentioned: | 2020 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://www.science.org/doi/10.1126/sciadv.aay9597 |
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