Compound ID | 2303
NL3
Class: Small molecule antibacterial agent
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Active against Staphylococcus aureus and Pseudomonas aeruginosa; inhibits bacterial cystathionine γ-lyase that generates H2S (protects bacteria from oxidative stress) |
| Description: | Synthetic compound discovered from structure-based virtual screening; small molecule with pyrazole carboxylate central indole moiety |
| Year first mentioned: | 2021 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://www.science.org/doi/10.1126/science.abd8377 |
AntibioticDB is supported by GARDP.
If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions
The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.