Compound ID | 2313
Feleucin-K59 (K59)
Synonym(s): Feleucin K59
Class: Antimicrobial peptide
| Agent Type: | Synthetic; Direct acting; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Membrane-active agent. Disrupts integrity of cytoplasmic membrane and binds to DNA |
| Target Pathogen: | Active against Acinetobacter baumannii, Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa |
| Description: | Synthetic compound; analogue of feleucin-K3 an antimicrobial peptide from skin secretion of Bombina orientalis |
| Year first mentioned: | 2021 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://pubs.acs.org/doi/10.1021/acsinfecdis.0c00545 |
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