Compound ID | 232

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C11

Class: Quorum sensing inhibitor

Spectrum of activity: Gram-negative
Details of activity: Pseudomonas aeruginosa biofilm disruption
Combined with other compounds: Yes
Description: N-pyrimidyl butanamide
Institute where first reported: Faculte de Pharmacie, Toulouse, France
Year first mentioned: 2015
Highest developmental phase: Preclinical
Development status: Active
Chemical structure(s):
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Molecular weight: 165.19
Iso. SMILES: CCCC(=O)NC1=NC=CC=N1
InChI Key: LLOPBTAFNVCFOF-UHFFFAOYSA-N
Can. SMILES: CCCC(=O)NC1=NC=CC=N1
InChI: InChI=1S/C8H11N3O/c1-2-4-7(12)11-8-9-5-3-6-10-8/h3,5-6H,2,4H2,1H3,(H,9,10,11,12)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/4220870
Citations:
  • https://www.ncbi.nlm.nih.gov/pubmed/26711774
  • https://journals.asm.org/doi/10.1128/aac.02533-15

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