Compound ID | 2330

Update compound information

Bacillimidazole G

Class: Natural product antibiotic

Spectrum of activity: Gram-positive
Details of activity: Active against Lacticasei bacillus paracasei subsp. Paracasei, methicillin-resistant Staphylococcus aureus, and Acinetobacter baumannii ∆lpxC
Description: Natural product from probiotic Bacillus licheniformis; not cytotoxic to mammalian cell lines Wi38 (human foetal lung fibroblast cell line), Chang (human normal liver cell line), and NIH3T3 (mouse fibroblast cell line) at 100 uM (highest concentration tested) vs MIC at 1.56 uM (Gram-positive ) to 6.25 uM (Acinetobacter baumannii ∆lpxC)
Year first mentioned: 2023
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 425.59
Iso. SMILES: CC1=C(C)N(CCC2=CNC3=C2C=CC=C3)C(CCC)=[N+]1CCC4=CNC5=C4C=CC=C5
InChI Key: CELKXWDQNLWDDM-UHFFFAOYSA-N
Can. SMILES: CCCC1=[N+](CCC2=CNC3=C2C=CC=C3)C(=C(C)N1CCC4=CNC5=C4C=CC=C5)C
InChI: InChI=1S/C28H33N4/c1-4-9-28-31(16-14-22-18-29-26-12-7-5-10-24(22)26)20(2)21(3)32(28)17-15-23-19-30-27-13-8-6-11-25(23)27/h5-8,10-13,18-19,29-30H,4,9,14-17H2,1-3H3/q+1
External links:
Citation: https://pubs.acs.org/doi/10.1021/acs.jnatprod.2c01032

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.