Compound ID | 2342

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Fucomycin V

Synonym(s): Ravidomycin analogue 9

Class: Natural product antibiotic

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Pseudomonas aeruginosa and Staphylococcus aureus
Description: Natural product from Streptomyces sp. Am59; ravidomycin analogues reported; contains angucycline/ polyketide scaffold
Year first mentioned: 2023
Development status: Experimental
Chemical structure(s):
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Molecular weight: 494.49
Iso. SMILES: OC1=C2C(C=3OC(C4=C(C(OC)=CC(C=C)=C4)C3C=C2OC)=O)=C([C@@H]5O[C@H](C)[C@H](O)[C@H](O)[C@H]5O)C=C1
InChI Key: MSXWAMODDZJPTG-VYWDFFCBSA-N
Can. SMILES: C=CC1=CC2=C(C3=CC(=C4C(=CC=C(C4=C3OC2=O)[C@H]5[C@@H]([C@H]([C@H]([C@@H](C)O5)O)O)O)O)OC)C(=C1)OC
InChI: InChI=1S/C27H26O9/c1-5-12-8-15-19(17(9-12)33-3)14-10-18(34-4)21-16(28)7-6-13(20(21)25(14)36-27(15)32)26-24(31)23(30)22(29)11(2)35-26/h5-11,22-24,26,28-31H,1H2,2-4H3/t11-,22+,23+,24-,26+/m1/s1
External links:
Citation: https://pubs.acs.org/doi/10.1021/acs.jnatprod.3c00381

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