Compound ID | 2346

Triculamin

Synonym(s): Triculamine

Class: Antimicrobial peptide

Details of activity: Active against Mycobacterium phlei and Mycobacterium smegmatis; membrane-active agent
Description: Natural product from Streptomyces triculaminicus; no cytotoxic effect observed in human osteosarcoma cells, U-2OS, human pancreatic cancer cells, and non-cancer skin fibroblasts BJ; preclinical evaluation showed it is inferior to kanamycin in mouse model; a lasso peptide
Year first mentioned: 1958
Development status: Experimental

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