Compound ID | 2359
GE81112 B1
Class: Antimicrobial peptide
| Agent Type: | Semisynthetic; Direct acting; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Protein synthesis inhibitor. Inhibits bacterial translation initiation |
| Target Pathogen: | Active against Escherichia coli |
| Description: | Synthetic compound (tetrapeptide) based on natural product GE81112; analogues reported |
| Year first mentioned: | 2021 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://pubs.acs.org/doi/10.1021/jacs.0c13424 |
| Patent: | JP2005510573A |
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