Compound ID | 2365

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Benastatin B

Class: Natural product antibiotic

Agent Type: Natural product; Small molecule; Direct acting;
Spectrum of activity: Gram-positive
Mechanism of action: Cell wall synthesis inhibitor. Transglycosylase inhibitor
Target Pathogen: Active against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus
Description: Natural product from crude extracts library (extract 18894); aromatic polyketide (benastatin derivative) produced by Streptomyces sp.
Year first mentioned: 1992
Development status: Experimental
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/126409
Citations:
  • https://www.jstage.jst.go.jp/article/antibiotics1968/45/9/45_9_1385/_article
  • https://pubs.acs.org/doi/10.1021/jacs.7b13205

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