Compound ID | 2373
Maxamycin 21
Synonym(s): [Ψ[C(═NH)NH]Tpg4]vancomycin 21
Class: Glycopeptide
| Spectrum of activity: | Gram-positive |
| Details of activity: | Active against methicillin-resistant Staphylococcus aureus, and vancomycin-resistant Enterococcus faecium; inhibits cell wall synthesis, additionally permeabilizes membrane |
| Description: | Synthetic compound; no cytotoxicity observed against mammalian red blood cells at >250-fold above MIC |
| Year first mentioned: | 2023 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://pubs.acs.org/doi/10.1021/jacs.3c03710 |
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