Compound ID | 2375

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Dialkylamine 1

Class: Natural product antibiotic

Spectrum of activity: Gram-negative
Details of activity: Active against Escherichia coli and Acinetobacter baumannii
Description: Natural product; IC50 towards cytoplasmic and mitochondrial PheRS at >30 ug/ml vs IC50 towards Gram-negative PheRS at 3.5-20 ug/ml; analogues with antibacterial activity reported
Year first mentioned: 2021
Development status: Experimental
Chemical structure(s):
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Molecular weight: 215.33
Iso. SMILES: C1(CNCCC2=CCCCC2)=CC=CC=C1
InChI Key: RTJNHLXWVAXRBH-UHFFFAOYSA-N
Can. SMILES: C1CC=C(CC1)CCNCC2=CC=CC=C2
InChI: InChI=1S/C15H21N/c1-3-7-14(8-4-1)11-12-16-13-15-9-5-2-6-10-15/h2,5-7,9-10,16H,1,3-4,8,11-13H2
External links:
Citation: https://pubs.acs.org/doi/10.1021/jacs.0c11113

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