Compound ID | 2393

ApidaecinĀ 137

Synonym(s): Api137

Class: Antimicrobial peptide

Spectrum of activity: Gram-negative
Details of activity: Active against Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, Enterobacter cloacae, Proteus vulgaris, and Pseudomonas aeruginosa; inhibits protein synthesis
Description: Synthetic compound, a derivative of the natural product apidaecin from honeybees (Apis mellifera); no cytotoxicity towards HEK293, HepG2, and HeLa cells; analogues reported
Year first mentioned: 2013
Development status: Experimental

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