Compound ID | 2394
Anoplin A-21
Class: Antimicrobial peptide
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Active against Staphylococcus aureus, Enterococcus faecalis, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter baumannii; membrane-active agent |
| Description: | Synthetic compound, a derivative of the natural product anoplin from wasp (Anoplius samariensis) venom; showed weaker toxicity and comparable activity to polymyxin B in vivo; analogues with antibacterial properties reported |
| Year first mentioned: | 2021 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c00614 |
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