Compound ID | 2400
Dipicolylamine-containing carbazole derivatives combined with Zn2+
Class: Antimicrobial peptide
| Agent Type: | Synthetic; Direct acting; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Membrane-active agent |
| Target Pathogen: | Active against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, Escherichia coli, Acinetobacter baumannii, and Pseudomonas aeruginosa |
| Description: | Synthetic compound (peptidomimetic); analogues reported; addition of zinc aids in penetrating outer membrane; very low cytotoxicity towards mammalian cells |
| Year first mentioned: | 2021 |
| Development status: | Experimental |
| External links: | |
| Citations: |
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