Compound ID | 2400
Dipicolylamine-containing carbazole derivatives combined with Zn2+
Class: Antimicrobial peptide
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Active against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, Escherichia coli, Acinetobacter baumannii, and Pseudomonas aeruginosa; membrane-active agent (cytoplasmic membrane) |
| Description: | Synthetic compound (peptidomimetic); analogues reported; addition of zinc aids in penetrating outer membrane; very low cytotoxicity towards mammalian cells |
| Year first mentioned: | 2021 |
| Development status: | Experimental |
| External links: | |
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