Compound ID | 2404
Synonym(s): AAV qC10
Class: Glycopeptide
Spectrum of activity: | Gram-positive |
Details of activity: | Active against Staphylococcus aureus, vancomycin-resistant Staphylococcus aureus, and vancomycin-resistant Enterococci, inhibits cell wall synthesis and depolarizes/permeabilizes cell membrane |
Description: | Synthetic compound; 12% haemolysis of human erythrocytes at 250 uM (MIC 14.7 uM); analogues with antibacterial property reported |
Year first mentioned: | 2021 |
Development status: | Experimental |
External links: | |
Citation: | https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c00449 |