Compound ID | 2405
PrAMP Bac7 (1–16)
Synonym(s): B7-004, B7-005 and B7-002
Class: Antimicrobial peptide
| Agent Type: | Synthetic; Direct acting; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Membrane-active agent. Inhibits protein synthesis and depolarizes cell membrane |
| Target Pathogen: | Active against Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Staphylococcus aureus |
| Description: | Synthetic compound; no haemolytic effect against eukaryotic blood cells, tolerates serum proteases |
| Year first mentioned: | 2020 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00665 |
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