Compound ID | 242
TP-138
Class: Tetracycline
| Spectrum of activity: | Gram-negative |
| Details of activity: | Carbapenem-resistant Enterobacteriaceae (CRE) and multidrug-resistant Acinetobacter |
| Propensity to select resistant mutants: | Yes |
| Description: | In Vivo Efficacy of Novel, Fully Synthetic Tetracyclines in a Murine Lung Infection Model Challenged with KPC-producing Klebsiella pneumoniae T. Grossman, C. Fyfe, K. Kerstein, C. Sun, D. Hunt, R. Clark, X. Xiao, J. Sutcliffe |
| Institute where first reported: | Tetraphase Pharmaceuticals, USA |
| Year first mentioned: | 2014 |
| Highest developmental phase: | Preclinical |
| Development status: | Active |
| External links: | |
| Citation: |
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