Compound ID | 2428

Update compound information

5-Amino-4-quinolone 111, antibacterial agent 123

Class: Quinolone

Spectrum of activity: Gram-positive
Details of activity: Active against Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, and Enterococcus faecium
Description: Synthetic compound; 500-fold selectivity towards bacterial membrane
Year first mentioned: 2022
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 441.25
Iso. SMILES: C1=CC(=NC=C1C(F)(F)F)NC2=CC(=CC3=C2C(=O)C=C(N3)C(F)(F)F)C(F)(F)F
InChI Key: RYODTJWRFFACTO-UHFFFAOYSA-N
Can. SMILES: C1=C(C=NC(=C1)NC2=C3C(=CC(=C2)C(F)(F)F)NC(=CC3=O)C(F)(F)F)C(F)(F)F
InChI: InChI=1S/C17H8F9N3O/c18-15(19,20)7-1-2-13(27-6-7)29-10-4-8(16(21,22)23)3-9-14(10)11(30)5-12(28-9)17(24,25)26/h1-6H,(H,27,29)(H,28,30)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/165413023
Citation: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01151

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.