Compound ID | 243
TP-600
Class: Tetracycline
| Agent Type: | Synthetic; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Unknown |
| Target Pathogen: | Active against carbapenem-resistant Enterobacteriaceae and multidrug-resistant Acinetobacter |
| Propensity to select resistant mutants: | Yes |
| Description: | In Vivo Efficacy of Novel, Fully Synthetic Tetracyclines in a Murine Lung Infection Model Challenged with KPC-producing Klebsiella pneumoniae T. Grossman, C. Fyfe, K. Kerstein, C. Sun, D. Hunt, R. Clark, X. Xiao, J. Sutcliffe |
| Institute where first reported: | Tetraphase Pharmaceuticals, USA |
| Year first mentioned: | 2014 |
| Development status: | Experimental |
| External links: |
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