Compound ID | 2491
Tur1A
Class: Antimicrobial peptide
| Spectrum of activity: | Gram-negative |
| Details of activity: | Active against Escherichia coli; targets protein synthesis; internalised into Gram-negative membrane but can lyse membrane during prolonged incubation or higher concentrations (membrane-active agent) |
| Description: | Natural product found in Tursiops truncatus (bottlenose dolphin); a proline-rich peptide |
| Institute where first reported: | Gene Center, Department for Biochemistry and Center for Integrated Protein Sciences, Munich (CiPSM), University of Munich, 81377 Munich, Germany |
| Year first mentioned: | 2018 |
| Development status: | Experimental |
| External links: | |
| PubChem link: | https://pubchem.ncbi.nlm.nih.gov/substance/485480451 |
| Citation: | https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(18)30044-8 |
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