Compound ID | 2498
Tun-X,X
Synonym(s): Tunicamycin analogue
Class: Small molecule antibacterial agent
| Details of activity: | Active against Mycobacterium tuberculosis; inhibits MraY |
| Description: | Semisynthetic compound with core structure based on the natural product tunicamycin from Streptomyces coelicolor; no cytotoxicity towards eukaryotic cells |
| Institute where first reported: | Structural Genomics Consortium, University of Oxford, Oxford, OX3 7DQ, UK |
| Year first mentioned: | 2018 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://www.cell.com/cell/fulltext/S0092-8674(18)31393-X#secsectitle0035 |
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