Compound ID | 2502

Update compound information

Dephostatin

Class: Antivirulence agent

Agent Type: Natural product; Small molecule; Indirect acting; Antivirulence;
Spectrum of activity: Gram-negative
Target Pathogen: Active against Salmonella sp.
Description: Natural product without antibacterial activity but inhibits virulence factors and polymyxin resistance genes; potentiates polymyxin antibiotics
Year first mentioned: 2020
Development status: Experimental
Chemical structure(s):
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Molecular weight: 168.15
Iso. SMILES: CN(C1=C(C=CC(=C1)O)O)N=O
InChI Key: HCJOLYFWJWJPTJ-UHFFFAOYSA-N
Can. SMILES: CN(C1=CC(=CC=C1O)O)N=O
InChI: InChI=1S/C7H8N2O3/c1-9(8-12)6-4-5(10)2-3-7(6)11/h2-4,10-11H,1H3
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/2990
Citation: https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(20)30119-7

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