Compound ID | 2533

Update compound information

Blasticidin S

Class: Natural product antibiotic

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Pseudomonas fluorescens and Mycobacterium sp.; inhibits protein synthesis
Propensity to select resistant mutants: Yes
Description: Natural product from Streptomyces griseochromogenes; a peptidylnucleoside
Year first mentioned: 1957
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 422.44
Iso. SMILES: CN(CC[C@@H](CC(=O)N[C@H]1C=C[C@@H](O[C@@H]1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N
InChI Key: CXNPLSGKWMLZPZ-ZNIXKSQXSA-N
Can. SMILES: CN(CC[C@@H](CC(=O)N[C@H]1C=C[C@H](N2C=CC(=NC2=O)N)O[C@@H]1C(=O)O)N)C(=N)N
InChI: InChI=1S/C17H26N8O5/c1-24(16(20)21)6-4-9(18)8-12(26)22-10-2-3-13(30-14(10)15(27)28)25-7-5-11(19)23-17(25)29/h2-3,5,7,9-10,13-14H,4,6,8,18H2,1H3,(H3,20,21)(H,22,26)(H,27,28)(H2,19,23,29)/t9-,10-,13+,14-/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/170012
Citations:
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444127/
  • https://www.jstage.jst.go.jp/article/antibioticsa/11/1/11_1/_pdf

    • AntibioticDB is supported by GARDP.

    If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

    The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.