Compound ID | 2556

Update compound information

Fortimicin A

Synonym(s): Astromicin

Class: Aminoglycoside

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Escherichia coli, Enterobacter sp., Klebsiella pneumoniae, methicillin-resistant and -susceptible Staphylococcus aureus, Haemophilus influenzae
Description: Natural product from Micromonospora olivoastrospora; pseudodisaccharide with fortamine and aminocyclitol
Year first mentioned: 1981
Development status: Experimental
Chemical structure(s):
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Molecular weight: 405.49
Iso. SMILES: C[C@@H]([C@@H]1CC[C@H]([C@H](O1)O[C@@H]2[C@H]([C@@H]([C@@H]([C@H]([C@H]2O)N(C)C(=O)CN)OC)O)N)N)N
InChI Key: BIDUPMYXGFNAEJ-APGVDKLISA-N
Can. SMILES: C[C@@H]([C@@H]1CC[C@H]([C@H](O1)O[C@@H]2[C@H]([C@@H]([C@@H]([C@H]([C@H]2O)N(C)C(=O)CN)OC)O)N)N)N
InChI: InChI=1S/C17H35N5O6/c1-7(19)9-5-4-8(20)17(27-9)28-15-11(21)13(24)16(26-3)12(14(15)25)22(2)10(23)6-18/h7-9,11-17,24-25H,4-6,18-21H2,1-3H3/t7-,8+,9-,11-,12-,13-,14+,15+,16+,17+/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/5284517
Citations:
  • https://www.jstage.jst.go.jp/article/antibiotics1968/30/7/30_7_564/_pdf/-char/en
  • https://journals.asm.org/doi/10.1128/aac.19.1.122

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