Compound ID | 2583

Update compound information

Lactoquinomycin A

Synonym(s): Medermycin

Class: Natural product antibiotic

Agent Type: Natural product; Small molecule;
Spectrum of activity: Gram-positive
Mechanism of action: Unknown
Target Pathogen: Active against susceptible and multi-drug resistant staphylococci
Description: Natural product from Streptomyces tanashinensis
Year first mentioned: 1976
Development status: Experimental
Chemical structure(s):
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Molecular weight: 457.47
Iso. SMILES: CC1C(C(CC(O1)C2=C(C3=C(C=C2)C(=O)C4=C(C3=O)C(OC5C4OC(=O)C5)C)O)N(C)C)O
InChI Key: NYJGMJFBEVSQNN-UHFFFAOYSA-N
Can. SMILES: CC1C2=C(C(=O)C3=CC=C(C4CC(C(C(C)O4)O)N(C)C)C(=C3C2=O)O)C5C(CC(=O)O5)O1
InChI: InChI=1S/C24H27NO8/c1-9-17-19(24-15(31-9)8-16(26)33-24)22(29)12-6-5-11(21(28)18(12)23(17)30)14-7-13(25(3)4)20(27)10(2)32-14/h5-6,9-10,13-15,20,24,27-28H,7-8H2,1-4H3
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/124692
Citations:
  • https://pubs.acs.org/doi/10.1021/ol026222e
  • https://www.nature.com/articles/s41467-022-32901-0
  • https://www.jstage.jst.go.jp/article/antibiotics1968/29/7/29_7_765/_pdf/-char/en

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