Compound ID | 2605

Update compound information

9-propionylmaridomycin

Class: Macrolide

Spectrum of activity: Gram-positive
Details of activity: Active against Gram-positives; protein synthesis inhibitor
Description: Semisynthetic compound based from the natural product maridomycin produced by Streptomyces hygroscopicus
Institute where first reported: Takeda Chemical Ind. Ltd
Year first mentioned: 1972
Development status: Experimental
Chemical structure(s):
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Molecular weight: 914.09
Iso. SMILES: CCC(=O)OC1CC(=O)OC(CC2C(O2)/C=C/C(C(CC(C(C1OC)OC3C(C(C(C(O3)C)OC4CC(C(C(O4)C)OC(=O)CC(C)C)(C)O)N(C)C)O)CC=O)C)OC(=O)CC)C
InChI Key: YOEZGCFEDPFSHG-FOCLMDBBSA-N
Can. SMILES: CCC(=O)OC1/C=C/C2C(CC(C)OC(=O)CC(C(C(C(CC=O)CC1C)OC3C(C(C(C(C)O3)OC4CC(C)(C(C(C)O4)OC(=O)CC(C)C)O)N(C)C)O)OC)OC(=O)CC)O2
InChI: InChI=1S/C46H75NO17/c1-13-34(49)60-30-15-16-31-32(59-31)21-26(6)56-37(52)22-33(61-35(50)14-2)43(55-12)42(29(17-18-48)20-25(30)5)64-45-40(53)39(47(10)11)41(27(7)58-45)63-38-23-46(9,54)44(28(8)57-38)62-36(51)19-24(3)4/h15-16,18,24-33,38-45,53-54H,13-14,17,19-23H2,1-12H3/b16-15+
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/6445431
Citations:
  • https://journals.asm.org/doi/epdf/10.1128/aac.6.6.685
  • https://www.jstage.jst.go.jp/article/chemotherapy1953/21/5/21_5_1044/_pdf/-char/en
  • https://www.jstage.jst.go.jp/article/kansenshogakuzasshi1970/48/9/48_9_357/_article
  • https://journals.asm.org/doi/epdf/10.1128/aac.4.2.156

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