Compound ID | 2624

Update compound information

Minosaminomycin

Class: Aminoglycoside

Agent Type: Natural product; Small molecule; Direct acting;
Spectrum of activity: Antimycobacterial
Mechanism of action: Protein synthesis inhibitor. Shown in Escherichia coli cell-free system
Target Pathogen: Active against Mycobacterium smegmatis and Mycobacterium phlei
Description: Natural product from Streptomyces No. MA514-A1; contains myo-inosamine; structurally related to kasugamycin
Year first mentioned: 1974
Development status: Experimental
Chemical structure(s):
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Molecular weight: 618.68
Iso. SMILES: CC1C(CC(C(O1)OC2C(C(C(C(C2O)O)NC(=O)C(CC3CN=C(N3)N)NC(=O)NC(CC(C)C)C(=O)O)O)O)N)N
InChI Key: UDZJEGDQBWDMOF-UHFFFAOYSA-N
Can. SMILES: CC(C)CC(C(=O)O)NC(=O)NC(CC1CN=C(N)N1)C(=O)NC2C(C(C(C(C2O)O)OC3C(CC(C(C)O3)N)N)O)O
InChI: InChI=1S/C25H46N8O10/c1-8(2)4-14(22(39)40)32-25(41)31-13(5-10-7-29-24(28)30-10)21(38)33-15-16(34)18(36)20(19(37)17(15)35)43-23-12(27)6-11(26)9(3)42-23/h8-20,23,34-37H,4-7,26-27H2,1-3H3,(H,33,38)(H,39,40)(H3,28,29,30)(H2,31,32,41)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/197190
Citations:
  • https://www.jstage.jst.go.jp/article/antibiotics1968/30/2/30_2_132/_pdf/-char/en
  • https://www.jstage.jst.go.jp/article/antibiotics1968/27/1/27_1_81/_pdf/-char/en

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