Compound ID | 2630

Update compound information

Marcellomycin

Class: Natural product antibiotic

Spectrum of activity: Gram-positive
Details of activity: Active against Streptococcus pneumoniae, Streptococcus pyogenes, and Staphylococcus aureus
Description: Natural product from Actinosporangium sp.; also shows anti-tumour properties in mice; an anthracycline
Institute where first reported: Research Division, Bristol Laboratories, Division of Bristol Myers Company, Syracuse, N. Y., U. S. A
Year first mentioned: 1977
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 845.88
Iso. SMILES: CC[C@]1(C[C@@H](C2=C(C3=C(C=C2[C@H]1C(=O)OC)C(=O)C4=C(C=CC(=C4C3=O)O)O)O)O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O[C@H]6C[C@@H]([C@@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@@H]([C@@H](O7)C)O)O)O)N(C)C)O
InChI Key: VJRAUFKOOPNFIQ-TVEKBUMESA-N
Can. SMILES: CC[C@]1(C[C@@H](C2=C(C=C3C(=C2O)C(=O)C4=C(C(=CC=C4O)O)C3=O)[C@H]1C(=O)OC)O[C@H]5C[C@@H]([C@@H]([C@H](C)O5)O[C@H]6C[C@@H]([C@@H]([C@H](C)O6)O[C@H]7C[C@@H]([C@@H]([C@H](C)O7)O)O)O)N(C)C)O
InChI: InChI=1S/C42H55NO17/c1-8-42(53)15-26(30-19(34(42)41(52)54-7)11-20-31(37(30)50)38(51)33-23(45)10-9-22(44)32(33)36(20)49)58-27-12-21(43(5)6)39(17(3)56-27)59-29-14-25(47)40(18(4)57-29)60-28-13-24(46)35(48)16(2)55-28/h9-11,16-18,21,24-29,34-35,39-40,44-48,50,53H,8,12-15H2,1-7H3/t16-,17-,18-,21-,24-,25-,26-,27-,28-,29-,34-,35+,39+,40+,42+/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/107861
Citations:
  • https://www.jstage.jst.go.jp/article/antibiotics1968/30/6/30_6_519/_pdf
  • https://www.jstage.jst.go.jp/article/antibiotics1968/30/6/30_6_525/_pdf/-char/en
    • Patent: US4064014A

    AntibioticDB is supported by GARDP.

    If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

    The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.