Compound ID | 2632

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Mutamicin

Class: Aminoglycoside

Agent Type: Natural product; Small molecule;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Unknown
Target Pathogen: Active against Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Salmonella typhimurium
Description: Natural product from a mutant Micromonospora inyoensis; requires the addition of 2-deoxystreptamine analogues or streptamine in media for compound to be produced
Institute where first reported: Microbiological and Medicinal Chemistry Divisions, Schering Corporation, Bloomfield, N. J., 07003 U.S.A.
Year first mentioned: 1974
Development status: Experimental
Chemical structure(s):
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Molecular weight: 463.53
Iso. SMILES: CC1(COC(C(C1NC)O)OC2C(C(C(C(C2O)OC3C(CC=C(O3)CN)N)N)O)N)O
InChI Key: GCLCARAXIXZEAH-UHFFFAOYSA-N
Can. SMILES: CC1(COC(C(C1NC)O)OC2C(C(C(C(C2O)OC3C(CC=C(CN)O3)N)N)O)N)O
InChI: InChI=1S/C19H37N5O8/c1-19(28)6-29-18(13(27)16(19)24-2)32-15-10(23)11(25)9(22)14(12(15)26)31-17-8(21)4-3-7(5-20)30-17/h3,8-18,24-28H,4-6,20-23H2,1-2H3
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/3042922
Citation: https://www.jstage.jst.go.jp/article/antibiotics1968/27/12/27_12_917/_pdf

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