Compound ID | 2639

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Naphthyridinomycin

Class: Natural product antibiotic

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Staphylococcus aureus, Streptococcus faecalis, Escherichia coli, Enterobacter aerogenes, Salmonella pullorum, Pseudomonas aeruginosa, Pseudomonas fluorescens, Proteus mirabilis, Proteus vulgaris, Klebsiella pneumoniae, and Serratia marcescens; DNA synthesis inhibitor
Description: Natural product from Streptomyces lusitanus
Year first mentioned: 1975
Development status: Experimental
Chemical structure(s):
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Molecular weight: 417.46
Iso. SMILES: CC1=C(C(=O)C2=C(C1=O)C3C4C5C(CC(N5C)[C@H](N4[C@@H]2CO)O)C6N3CCO6)OC
InChI Key: SXDWNOFDSOXRRM-DDMUOLFQSA-N
Can. SMILES: CC1=C(C(=O)C2=C(C3C4C5C(CC([C@H](N4[C@@H]2CO)O)N5C)C6N3CCO6)C1=O)OC
InChI: InChI=1S/C21H27N3O6/c1-8-17(26)13-12(18(27)19(8)29-3)11(7-25)24-16-14-9(6-10(20(24)28)22(14)2)21-23(15(13)16)4-5-30-21/h9-11,14-16,20-21,25,28H,4-7H2,1-3H3/t9?,10?,11-,14?,15?,16?,20-,21?/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/156580381
Citation: https://www.jstage.jst.go.jp/article/antibiotics1968/28/7/28_7_497/_pdf/-char/en

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