Compound ID | 2645

Update compound information

Netropsin

Synonym(s): Sinanomycin

Class: Natural product antibiotic

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Staphylococcus aureus, Salmonella sp., and Escherichia coli
Description: Natural product from Streptomyces netropsis; shows toxicity upon parenteral administration; contains pyrrole-amidine core
Institute where first reported: Research Laboratories of Chas. Pfizer and Co., Inc
Year first mentioned: 1951
Development status: Inactive
Chemical structure(s):
Click here for structure editor
Molecular weight: 430.46
Iso. SMILES: CN1C=C(C=C1C(=O)NC2=CN(C(=C2)C(=O)NCCC(=N)N)C)NC(=O)CN=C(N)N
InChI Key: IDBIFFKSXLYUOT-UHFFFAOYSA-N
Can. SMILES: CN1C=C(C=C1C(=O)NCCC(=N)N)NC(=O)C2=CC(=CN2C)NC(=O)CN=C(N)N
InChI: InChI=1S/C18H26N10O3/c1-27-9-11(6-12(27)16(30)23-4-3-14(19)20)26-17(31)13-5-10(8-28(13)2)25-15(29)7-24-18(21)22/h5-6,8-9H,3-4,7H2,1-2H3,(H3,19,20)(H,23,30)(H,25,29)(H,26,31)(H4,21,22,24)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/4461
Citation: https://pubs.acs.org/doi/epdf/10.1021/ja01145a113

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.