Compound ID | 267
Class: Oxazolidinone (azabicyclic analogue)
Spectrum of activity: | Gram-positive & Gram-negative |
Details of activity: | Protein synthesis inhibitors; improved potency against Gram positive bacteria and fastidious Gram negative compared with linezolid |
Description: | Renslo AR, Gao H, Jaishankar P, et al. Synthesis and antimicrobial activity of novel oxa-, aza-, and thiabicyclo[3.1.0]hexylphenyl oxazolidinone analogs. 45th-Intersci-Conf-Antimicrob-Agents-Chemother 2005;19 |
Institute where first reported: | Vicuron Pharmaceuticals (Durata Pharmaceuticals, USA) |
Year first mentioned: | 2005 |
Highest developmental phase: | Preclinical |
Development status: | Inactive |
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