Compound ID | 267
Class: Oxazolidinone (azabicyclic analogue)
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Protein synthesis inhibitors; improved potency against Gram positive bacteria and fastidious Gram negative compared with linezolid |
| Description: | Renslo AR, Gao H, Jaishankar P, et al. Synthesis and antimicrobial activity of novel oxa-, aza-, and thiabicyclo[3.1.0]hexylphenyl oxazolidinone analogs. 45th-Intersci-Conf-Antimicrob-Agents-Chemother 2005;19 |
| Institute where first reported: | Vicuron Pharmaceuticals (Durata Pharmaceuticals, USA) |
| Year first mentioned: | 2005 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
| External links: | |
| Citation: |