Compound ID | 267
Class: Oxazolidinone
| Agent Type: | Synthetic; Direct acting; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Protein synthesis inhibitor |
| Target Pathogen: | Broad spectrum activity |
| Description: | Improved potency compared to linezolid; Renslo AR, Gao H, Jaishankar P, et al. Synthesis and antimicrobial activity of novel oxa-, aza-, and thiabicyclo[3.1.0]hexylphenyl oxazolidinone analogues. 45th-Intersci-Conf-Antimicrob-Agents-Chemother 2005;19 |
| Institute where first reported: | Vicuron Pharmaceuticals (Durata Pharmaceuticals, USA) |
| Year first mentioned: | 2005 |
| Development status: | Experimental |
| External links: |