Compound ID | 2670

Update compound information

Prodigiosin

Class: Natural product antibiotic

Agent Type: Natural product; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Membrane-active agent. Likely disrupts integrity of cell membrane and induces generation of ROS
Target Pathogen: Active against Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa, Escherichia coli, Enterobacter cloacae, and Klebsiella aerogenes
Description: Natural product from Chromobacterium prodigiosum
Year first mentioned: 1946
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 323.43
Iso. SMILES: CCCCCC1=C(NC(=C1)/C=C\2/C(=CC(=N2)C3=CC=CN3)OC)C
InChI Key: SHUNBVWMKSXXOM-UNOMPAQXSA-N
Can. SMILES: CCCCCC1=C(C)NC(=C1)/C=C\2/C(=CC(=N2)C3=CC=CN3)OC
InChI: InChI=1S/C20H25N3O/c1-4-5-6-8-15-11-16(22-14(15)2)12-19-20(24-3)13-18(23-19)17-9-7-10-21-17/h7,9-13,21-22H,4-6,8H2,1-3H3/b19-12-
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/135455579
Citations:
  • https://jbioleng.biomedcentral.com/articles/10.1186/s13036-021-00262-9
  • https://www.frontiersin.org/articles/10.3389/fmicb.2016.00972/full
  • https://journals.asm.org/doi/10.1128/jb.52.1.145-146.1946

    • AntibioticDB is supported by GARDP.

    If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

    The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.