Compound ID | 2677
Polymyxin F
Class: Lipopeptide
| Agent Type: | Natural product; Direct acting; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Membrane-active agent. Disrupts integrity of cell membrane |
| Target Pathogen: | Active against Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, and Pseudomonas aeruginosa |
| Description: | Natural product from Bacillus circulans |
| Institute where first reported: | Squibb Institute for Medical Research P.O. Box 4000 Princeton, New Jersey 08540 U.S.A. |
| Year first mentioned: | 1977 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://www.jstage.jst.go.jp/article/antibiotics1968/30/9/30_9_767/_pdf/-char/en |
AntibioticDB is supported by GARDP.
If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions
The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.