Compound ID | 2677
Polymyxin F
Class: Lipopeptide
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Active against Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, and Pseudomonas aeruginosa; disrupts integrity of cell membrane |
| Description: | Natural product from Bacillus circulans |
| Institute where first reported: | Squibb Institute for Medical Research P.O. Box 4000 Princeton, New Jersey 08540 U.S.A. |
| Year first mentioned: | 1977 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://www.jstage.jst.go.jp/article/antibiotics1968/30/9/30_9_767/_pdf/-char/en |
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