Compound ID | 2679
Polymyxin P
Class: Antimicrobial peptide
| Agent Type: | Natural product; Direct acting; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Membrane-active agent. Disrupts integrity of cell membrane |
| Target Pathogen: | Active against Escherichia coli, Salmonella typhosa, Shigella flexneri, Shigella sonnei, Vibrio cholerae, Pseudomonas aeruginosa, and Klebsiella pneumoniae; slight activity towards Corynebacterium diphtheriae |
| Description: | Natural product from Bacillus polymyxa; active against phytopathogen Erwinia amylovora and Erwinia carotovora |
| Year first mentioned: | 1969 |
| Development status: | Experimental |
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